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#6

Top 100 Design-Build Firms (ENR)

 

 

 

 

6,000 +

Projects Completed Across North America

 

 

 

 

48

Offices Nationwide

 

 

 

 

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75 %

Repeat Client Revenue

 

 

 

 

Market Overview

ARCO/Murray partners with companies across the life sciences sector to deliver and expand complex manufacturing and production facilities, including radiopharmaceutical and other regulated environments. Our experience spans production operations, pilot-scale processing, and equipment-driven retrofits, where cleanroom classifications, process utilities, shielding, and equipment integration directly influence facility design and execution.

We design and build environments that require close coordination between process equipment and building infrastructure, aligning airflow, pressure relationships, utilities, and system interfaces to maintain controlled conditions, support compliance, and ensure consistent operational performance.

 

 

 

 

Our Approach

Design-build accelerates delivery on complex life sciences projects by integrating engineering, procurement, and construction early, when decisions around process equipment, utilities, and facility infrastructure define the path to startup. This approach aligns layout, shielding, cleanroom classifications, and mechanical and electrical systems with regulatory frameworks such as 21 CFR 211, 212, and EU Annex 1, allowing teams to resolve equipment integration, utility capacity, and compliance requirements upfront rather than during construction.

For programs where speed to production is critical, this level of coordination enables parallel design and construction, reduces rework at system interfaces, and supports a faster path through commissioning, qualification, and operational readiness.

 

 

 

  • Single Point of Accountability
    One contract and one integrated team coordinating design, procurement, and construction, enabling parallel execution across multiple facilities and supporting faster, more consistent rollout from concept through commissioning.

     

     

     

  • Upfront Budget Commitment
    We align the budget during design by defining and pricing process utilities, major MEP systems, and equipment early—establishing a reliable cost basis, coordinating procurement, and avoiding late-stage redesign and conflicts.

     

     

     

  • Accelerated Project Delivery

    Overlapping design, procurement, and construction allows early release of critical packages, coordination of long-lead equipment, and parallel execution of workstreams, enabling life sciences companies to bring new production capacity online faster.

     

     

     

  • Process & Infrastructure Integration

    Facility design is coordinated around process equipment and building infrastructure, aligning utilities, airflow, pressure relationships, and system interfaces early so equipment, systems, and spaces function as an integrated operation and perform reliably at startup.

     

     

     

  • Regulated Environment Expertise

    Cleanrooms, controlled environments, and specialized building systems are integrated to support compliance and long-term facility performance.

     

     

     

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